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Devil’s Club Monograph and Therapeutic Compendium

Home AHP Projects Support AHP’s Monograph Development Devil’s Club Monograph and Therapeutic Compendium
  • FUNDED $1,296
  • NEEDED $16,704
  • GOAL $18,000
  • FUNDED 7%


AHP’s Devil’s club (Oplopanax horridus) Monograph and Therapeutic Compendium

The American Herbal Pharmacopoeia (AHP) is proposing to develop an AHP Monograph and Therapeutic Compendium for devil’s club (Oplopanax horridus). Devil’s club has a tradition of both therapeutic and ceremonial use among Native American indigenous cultures. Although a member of the Araliaceae family, chemically related to Panax spp., and often marketed as a type of “ginseng,” medicinal properties similar to true ginseng have not been substantiated. While there is a potential for increasing demand of devil’s club, its sensitivity to over-harvesting and potential lack of accessibility to Native people’s is a concern. This will be a historic monograph as no other similar work of devil’s club has ever been done and it exists in no other pharmacopoeia. According to Eric Yarnell, Professor of Botanical Medicine at Bastyr University, “Oplopanax is the most revered medicine of the Pacific coast Native people, and AHP is uniquely positioned to combine the wealth of traditional knowledge with the scientific research on this widely used herb not currently documented in any modern monograph.”

AHP monographs represent the most comprehensive and critically reviewed body of information on herbal medicines in the English language, and serve as a primary reference for academicians, health care providers, manufacturers, and regulators. All AHP monographs are developed by acknowledged experts in the field of medicinal plants and include a diverse array of experts in botany, pharmacognosy, natural products chemistry and analysis, pharmacology, toxicology, and traditional herbal medicine. As with all AHP monographs, a suite of scientifically valid identification tests will be provided, along with appropriate drawings and photographic images to help in the identification of the species, along with guidance on sustainable harvesting practices.

We hope you will sincerely consider making a contribution to this important work. For herbal products manufacturers, we invite companies with Oplopanax expertise to review various sections of the monograph and will be listed as reviewers. We encourage sponsors to press release their support of the monograph at the time of sponsorship and again when the monograph is released. In addition, you would be able to include your sponsorship on your website, in presentations, and publications. If your material meets the standards established in the monograph, you would be able to promote your product as Devil’s Club AHP, which may set it apart from others in the industry. For individuals wishing to contribute, you will be participating in the furtherance of our knowledge base on herbal medicine for future generations, this is very fitting for this important North American botanical.

Please do not hesitate to contact us with any questions or for additional information.


Roy Upton, President
American Herbal Pharmacopoeia

Table of Contents


  • Botanical Nomenclature
  • Botanical Family
  • Pharmaceutical Nomenclature
  • Definition
  • Common Names


  • Botanical Identification
  • Macroscopic Identification
  • Microscopic Identification




  • Clinical Efficacy and Pharmacodynamics
  • Actions
  • Medical Indications Supported by Clinical Trials
  • Medical Indications Supported by Traditional or Modern Experience
  • Substantiation for Structure and Function Claims
  • Dosages

International Status


Commercial Sources & Handling

  • Collection
  • Cultivation
  • Handling and Processing
  • Drying
  • Storage
  • Qualitative Differentiation
  • Adulterants
  • Preparations
  • Environmental Sustainability


  • Thin Layer Chromatography (TLC/HPTLC)
  • Quantitative Standards

Safety Profile

  • Side Effects
  • Contraindications
  • Interactions
  • Pregnancy, Mutagenicity, and Reproductive Toxicity
  • Lactation
  • Carcinogenicity
  • Influence on Driving
  • Precautions
  • Overdose
  • Treatment of Overdose
  • Toxicology
  • Classification of the American Herbal Products Association



Devil’s Club Monograph Donation Form

$46 of $18,000 raised

* Please note: The full sponsorship goal of the Devil’s Club Monograph project is $18,000. If you would like to donate the full sponsorship amount, please contact us and we’ll send you an invoice.

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Donation Total: $50.00